Robert A Pufahl Selected Research

4- (3- (4- (1- methyl- 1H- pyrazol- 5- yl)phenylthio)phenyl)- tetrahydro- 2H- pyran- 4- carboxamide

7/2010

Pharmacology of PF-4191834, a novel, selective non-redox 5-lipoxygenase inhibitor effective in inflammation and pain.

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Robert A Pufahl Research Topics

Disease

3	Asthma (Bronchial Asthma) 07/2010 - 04/2008
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2015 - 01/2013
2	Inflammation (Inflammations) 07/2010 - 04/2008
2	Pain (Aches) 07/2010 - 09/2009
1	Neoplasms (Cancer) 01/2013
1	Liver Cirrhosis (Hepatic Cirrhosis) 04/2008
1	Rheumatoid Arthritis 04/2008
1	Atherosclerosis 04/2008
1	Cancer Pain 04/2008

Drug/Important Bio-Agent (IBA)

3	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 07/2010 - 04/2008
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2015 - 01/2013
2	LeukotrienesIBA 07/2010 - 09/2009
2	CarrageenanIBA 09/2009 - 04/2008
1	AZD 6244IBA 01/2013
1	2- (1H- indazol- 4- yl)- 6- (4- methanesulfonylpiperazin- 1- ylmethyl)- 4- morpholin- 4- ylthieno(3,2- d)pyrimidineIBA 01/2013
1	Lipoxygenase InhibitorsIBA 07/2010
1	4- (3- (4- (1- methyl- 1H- pyrazol- 5- yl)phenylthio)phenyl)- tetrahydro- 2H- pyran- 4- carboxamideIBA 07/2010
1	LipidsIBA 07/2010
1	EnzymesIBA 07/2010
1	Arachidonic Acid (Vitamin F)IBA 07/2010
1	zileuton (Zyflo)FDA Link 09/2009
1	Chelating AgentsIBA 09/2009
1	Freund's AdjuvantIBA 09/2009
1	IronIBA 09/2009
1	Leukotriene Antagonists (Leukotriene Receptor Antagonists)IBA 09/2009
1	ProstaglandinsIBA 04/2008

Therapy/Procedure

1	Therapeutics 01/2013